See important information below about the risk of hepatitis B virus reactivation.


After your treatment

If you've completed your hep C treatment, it's quite an accomplishment and something you should be proud of.

Am I cured?

Now that you’re done with your treatment, you may be wondering how your health care provider will know if you are cured. In order to determine if you are hep C free, your health care provider has to give you a blood test. Cure means the hep C virus is not detected in the blood when measured 3 months after treatment is completed.

If I am cured, can I get hep C again?

It’s important to keep in mind that you can still be reinfected with the hep C virus. If you are cured, follow your health care provider's advice about how to reduce the risk of reinfection.

To reduce the risk of reinfection, you should:

  • Avoid sharing needles or blood sugar meters

  • Avoid sharing personal items such as razors, toothbrushes, or nail clippers

  • Make sure tattoos and piercings are done in a place using sterile tools

  • Avoid having unprotected sex


Beyond treatment

Now more than ever, it's important to stay motivated to maintain
a healthy lifestyle.

Now that you've finished your treatment, you want to keep your liver in its best shape possible. That means:

  • Avoid alcohol

  • If you have a lot of liver scarring, follow up with your health care provider as directed

  • Continue to stay at a healthy body weight

  • If you have diabetes, make sure you control your blood sugar

  • Make sure your cholesterol and fats are within the range your health care provider recommends

Ask your health care team questions and talk about any concerns or challenges you may be having.

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ZEPATIER® (elbasvir and grazoprevir) is a prescription medicine used to treat chronic (long‑lasting) hepatitis C (hep C) genotypes 1 or 4 infection in adults. ZEPATIER may sometimes be given with another medicine called ribavirin.

Important Safety Information

Before starting treatment with ZEPATIER® (elbasvir and grazoprevir), your health care provider will do blood tests to check for hepatitis B virus infection. If you have ever had hepatitis B virus infection, the hepatitis B virus could become active again during or after treatment of hep C virus infection with ZEPATIER. This is called hepatitis B virus reactivation, and it may cause serious liver problems including liver failure and death. Your health care provider will monitor you if you are at risk for hepatitis B virus reactivation during treatment and after you stop taking ZEPATIER.

ZEPATIER is not for people with certain liver problems. Before taking ZEPATIER, tell your health care provider about all of your medical conditions, including if you have ever had hepatitis B virus infection or have liver problems other than hep C. Also tell your health care provider if you have ever taken any medicine for hep C, have HIV, or have had or are waiting for a liver transplant.

If you are nursing, pregnant, or trying to get pregnant, tell your health care provider. It is not known if ZEPATIER® (elbasvir and grazoprevir) will harm your unborn baby or pass to your baby through breast milk. If you take ZEPATIER with ribavirin, be sure you read the Medication Guide for ribavirin, especially the important pregnancy, contraception, and infertility information.

Tell your health care provider about all of the medicines you take. ZEPATIER may affect how other medicines work, and other medicines may affect how ZEPATIER works. Some medicines cannot be taken with ZEPATIER. Your health care provider can tell you if it is safe to take ZEPATIER with other medicines.

ZEPATIER may cause increases in your liver-related blood tests, which could be a sign of serious liver problems. Your health care provider will do blood tests to check your liver before and during treatment with ZEPATIER. Tell your health care provider right away if you get any of the following symptoms or if they get worse during treatment with ZEPATIER: loss of appetite, nausea and vomiting, feeling tired or weak, yellowing of your skin or eyes, or color changes in your stool.

In clinical studies, common side effects of ZEPATIER included: feeling tired, headache, and nausea. When ZEPATIER was taken with ribavirin, common side effects also included low red blood cell counts (called anemia).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1‑800‑FDA‑1088.

Before taking ZEPATIER® (elbasvir and grazoprevir), please read the accompanying Patient Information, including information about the risk of the hepatitis B virus (HBV) becoming active again in patients who have ever had HBV infection, and discuss it with your doctor. The Prescribing Information also is available.

Questions about ZEPATIER?
Call 844-ZEPATIER (844‑937‑2843)
for more information.

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